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Interjection butter my butt and call me a biscuit 1. (Southern US, colloquial) An expression of astonishment upon learning something unbelievable; chiefly something positive. [synonyms ] [quotations] Synonyms:slap my ass and call me Judy, slap my ass and call me Sally dip me in honey and throw me to the lesbians; see also Thesaurus:wow